|
|
H2O + filaggrin_L-Arg <=> protein_L-citrulline + NH3
|
3.5.3.15
protein-arginine deiminase
|
–
|
M
|
| |
BRENDA:
BR22725
KEGG:
R02621
MetaCyc:
PROTEIN-ARGININE-DEIMINASE-RXN
|
|
|
|
protein-Nomega-(ADP-D-ribosyl)-L-arginine + H2O <=> ADP-ribose + filaggrin_L-Arg
|
3.2.2.19
[protein ADP-ribosylarginine] hydrolase
|
–
|
|
| |
BRENDA:
BR50557
KEGG:
R07626
MetaCyc:
ADP-RIBOSYLARGININE-HYDROLASE-RXN
|
|
|
|
filaggrin_L-Arg + ATP <=> Protein_N(omega)-phospho-L-arginine + ADP + H+
|
2.7.14.1
protein arginine kinase
|
–
|
|
| |
BRENDA:
BR51087
KEGG:
R11090
MetaCyc:
RXN8J2-140
|
|
|
|
Protein_N(omega)-phospho-L-arginine + H2O <=> filaggrin_L-Arg + phosphate
|
3.9.1.2
protein arginine phosphatase
|
–
|
|
| |
BRENDA:
BR51156
KEGG:
R11095
MetaCyc:
RXN8J2-139
|
|
|
|
S-adenosyl-L-methionine + filaggrin_L-Arg <=> S-adenosyl-L-homocysteine + [protein]-Nomega,N''omega-dimethyl-L-arginine + H+
|
2.1.1.319
type I protein arginine methyltransferase
2.1.1.320
type II protein arginine methyltransferase
|
–
–
|
|
| |
BRENDA:
BR51514;
BR51517
MetaCyc:
RXN-17120;
RXN-17121
|
|
|
|
S-adenosyl-L-methionine + filaggrin_L-Arg <=> S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine + H+
|
2.1.1.319
type I protein arginine methyltransferase
2.1.1.320
type II protein arginine methyltransferase
2.1.1.321
type III protein arginine methyltransferase
|
–
–
–
|
|
| |
BRENDA:
BR51515
MetaCyc:
RXN-16889
|
|
|
|
S-adenosyl-L-methionine + filaggrin_L-Arg <=> S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine + H+
|
2.1.1.322
type IV protein arginine methyltransferase
|
–
|
|
| |
BRENDA:
BR51519
MetaCyc:
RXN-16890
|
|
|
|
filaggrin_L-Arg + O2 + 2-oxoglutarate <=> [protein]-(3R)-3-hydroxy-L-arginine + succinate + CO2
|
1.14.11.73
[protein]-arginine 3-hydroxylase
|
–
|
|
| |
BRENDA:
BR53101
KEGG:
R12645
MetaCyc:
RXN-20590
|
|
|
|
filaggrin_L-Arg + NAD+ <=> protein-Nomega-(ADP-D-ribosyl)-L-arginine + nicotinamide + H+
|
2.4.2.31
NAD+---protein-arginine ADP-ribosyltransferase
|
–
|
|
| |
BRENDA:
BS434705
KEGG:
R00555
MetaCyc:
2.4.2.31-RXN
|
|
|
|
methylglyoxal + filaggrin_L-Arg <=> an_Nomega-(1-hydroxy-2-oxopropyl)-[protein]-L-arginine
|
not assigned
|
–
|
|
| |
MetaCyc:
RXN-17629
|
|
|
|
an_Nomega-(1-hydroxy-2-oxopropyl)-[protein]-L-arginine + H2O <=> filaggrin_L-Arg + D-lactate + H+
|
3.5.1.124
protein deglycase
|
–
|
|
| |
MetaCyc:
RXN-17630
|
|
|
|
[protein]-Nomega-methyl-L-arginine + O2 + 2-oxoglutarate <=> filaggrin_L-Arg + succinate + CO2 + formaldehyde
|
not assigned
|
–
|
|
| |
MetaCyc:
RXN-20592
|
|
|
|
[protein]-Nomega,N''omega-dimethyl-L-arginine + O2 + 2-oxoglutarate <=> filaggrin_L-Arg + succinate + CO2 + formaldehyde
|
1.14.11.M17
|
–
|
|
| |
MetaCyc:
RXN-20595
|
|
|
|
[protein]-Nomega,Nomega-dimethyl-L-arginine + O2 + 2-oxoglutarate <=> filaggrin_L-Arg + succinate + CO2 + formaldehyde
|
1.14.11.M18
|
–
|
|
| |
MetaCyc:
RXN-20597
|
|
|
|
filaggrin_L-Arg + H2O <=> filaggrin_citrulline + NH3
|
3.5.3.15
protein-arginine deiminase
|
–
|
|
| |
BRENDA:
BS405148
|
|
|
|
filaggrin_L-Arg + H2O <=> filaggrin-L-citrulline + NH3
|
3.5.3.15
protein-arginine deiminase
|
–
|
|
| |
BRENDA:
BS405149
|
|
|
|
S-adenosyl-L-methionine + filaggrin_L-Arg <=> S-adenosyl-L-homocysteine + [protein]-Nomega-dimethyl-L-arginine
|
2.1.1.321
type III protein arginine methyltransferase
|
–
|
|
| |
BRENDA:
BS456647
|
|
